Microbiology-PTM-OMA_Modules_1-5

Overview • The Matrix Study determines the method performance in the claimed  matrices. • Matrix Studies for microbiology are typically a method comparison  between the candidate method and an appropriate reference method  for each matrix. • In rare cases, a reference method may not exist. • Method comparisons can be paired studies or unpaired studies. • Paired: Same enrichment or sample preparation procedure used for both  methods. Both methods analyze the same test portion. • Unpaired: Different enrichment or sample preparation procedures used for  the candidate and reference methods. The two methods analyze distinct test  portions.