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OMB MEETING MATERIALS

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Limit of Detection (LOD)

Discussion  Source: Guidelines for Single Laboratory Validation (SLV) of Chemical Methods for Metals in Food  Limit of Detection (LOD ): The lowest concentration of analyte in a sample that can be detected, but not necessarily quantitated under the stated conditions of the test.  Limit of Detection : “The true net concentration or amount of the analyte in the material to be analyzed which will lead, with probability (1-β), to the conclusion that the concentration or amount of the analyte in the analyzed material is larger than that in the blank material.

08/09/2018