OMB First to Final Action Recommendation Checklist 11-12-18

AOAC RESEARCH INSTITUTE Expert Review Panel Chair Report for Pesticide Residues Page 3 of 4

EXPERT REVIEW PANEL, METHOD BACKGROUND, AND CONCLUSIONS

Criteria for Vetting Methods to be considered: AOAC convened the Official Methods of Analysis SM (OMA) Expert Review Panel for Pesticide Residues on Monday, September 8, 2014 from 4:30pm to 7:30pm during the AOAC Annual Meeting and Exposition in Boca Raton, Florida. The purpose of the meeting was to 1) Review the Collaborative Study Manuscript/ OMAMAN-14: High-Throughput Analytical Techniques For The Determination And Confirmation Of Residues Of 653 Multi-Class Pesticides And Chemical Pollutants In Tea By GC-MS, GC-MS/MS And LC-MS/MS (Study Director: Guo-Fang Pang, Chun-Lin Fan,Yan-Zhong Cao, Fang Yang, Yan Li, Jian Kang, Hui Chen, Qiao-Ying Chang, Chinese Academy of Inspection and Quarantine, No. 3 Gaobeidian North Rd 100123, Chaoyang District, Beijing, People’s Republic of China) and to 2) discuss First to Final Action requirements and feedback mechanisms. The candidate method was reviewed against the approved collaborative study protocol. Supplemental information was also provided to the reviewers which included the collaborative study manuscript, Appendix 1.1-1.5 Analytical Instrumentation used in the Collaborative Study, Appendix 2 Determination Results of Collaborative Study, Appendix 3: Results of Practice Samples, Appendix 4: The Statistical Results, and an Journal Article: High-Throughput GC-MS and HPLC- MS/MS Techniques for the Multiclass, multiresidue Determination of 653 Pesticides and Chemical Pollutants in Tea. Criteria for Vetting Experts and Selection Process: The following seven (7) candidates and one (1) alternate member were submitted for consideration by the Official Methods Board to evaluate candidate methods for Pesticide Residues methods as per the Expert Review Panel (ERP) Policies and Procedures. The candidates were highly recommended by the Chemical Contaminants and Residues in Foods Community, have participated in various AOAC activities, including but limited to, Method Centric Committees that were formed under the legacy OMA pathway, and were vetted by the Official Methods Board. The experts are Amy Brown, Jo Marie Cook (Alternate), Julie Kowalski, John Reuther, Marina Torres, Jian Wang, and Xiaoyan Wang. ERP Orientation: The ERP members have completed the mandatory AOAC Expert Review Panel Orientation Webinar on Wednesday, July 16, 2014. Expert Review Panel Meeting Quorum The meeting of the Expert Review Panel was held in person. A quorum is the presence of seven (7) members or 2/3 of the total vetted ERP, whichever is greater. Seven (7) out of the seven (7) voting members were present and therefore met a quorum to conduct the meeting.

Standard Method Performance Requirements (SMPRs): N/A

Conclusion: The Expert Review Panel reviewed OMAMAN-14: High-Throughput Analytical Techniques For The Determination And Confirmation Of Residues Of 653 Multi-Class Pesticides And Chemical Pollutants In Tea By GC-MS, GC- MS/MS And LC-MS/MS and adopted this method for First Action Official Method status by a unanimous decision with additional revisions as noted in the meeting minutes.

Subsequent ERP Activities: ERP members will continue to evaluate the method for 2 years.