OMB Meeting Book_9-11-14
Table 24: Reproducibility data for whey-based infant formula test sample
Sample ID: Sample 5 K-5692/V-4737 Analyte CMP
UMP
GMP
IMP
AMP
(mg hg -1 )
(mg hg -1 )
(mg hg -1 )
(mg hg -1 )
(mg hg -1 )
Laboratory
Rep-1
Rep-2
Rep-1
Rep-2
Rep-1
Rep-2
Rep-1 0.03 a
Rep-2 0.02 a
Rep-1
Rep-2
1 2
5.20 4.55
5.25 4.40
3.47 3.25
3.51 3.26
1.01 1.06
1.01 1.05
3.69 3.15
3.69 3.06
0.00
0.00
3
6.23
5.98
2.97
2.90
1.13
1.13
0.00
0.00
3.35
3.52
4
6.00 5.86 c
6.10 6.41 c
3.60
3.60
1.10
1.10
0.00 0.00 b
0.00 0.22 b
3.70
3.60
5
3.78
3.93
1.07
1.09
3.48
3.52
6
5.48
5.43
3.87
3.84
1.06
1.03
0.00
0.00
3.46
3.40
7
5.30
5.26
3.70
3.56
0.98
0.98
0.00
0.00
3.64
3.51
8
5.41
5.39
3.64
3.66
1.06
1.05
0.00
0.00
3.42
3.39
9
5.44
5.47
3.58
3.55
1.05
1.08
0.00
0.00
3.39
3.39
10
5.58
5.59
3.53
3.59
1.07 1.10 c
1.06 1.00 c
0.00
0.00
3.68
3.71
11
5.50
5.20
3.00
3.00
0.00
0.00
3.60
3.50
12
5.13
5.23
3.75
3.87
1.03
1.00
0.00
0.00
3.67
3.70
a Identified as Grubbs outlier; results removed from data set for statistical analysis. b Identified as Cochran outlier; results removed from data set for statistical analysis. c Identified as Cochran outlier; results kept in data set for statistical analysis.
Table 25: Reproducibility analysis for whey-based infant formula test sample
Sample ID: Sample 5 K-5692/V-4737
CMP
UMP
GMP
IMP
AMP
Analyte Symbol
Seq.
Item
Value
Value
Value
Value
Value
10 a
1
Total number of laboratories
n
12
12
12
12
2
Total number of replicates
2n
24
24
24
18
24
3
Overall mean of all data (grand mean)
5.47
3.52
1.05
n/a
3.51
4
Repeatability standard deviation
Sr
0.15
0.05
0.02
n/a
0.06
5
Reproducibility standard deviation
SR
0.48
0.31
0.04
n/a
0.18
6
Repeatability limit in SMPR
≤6%
≤6%
≤6%
n/a
≤6%
7
Repeatability relative standard deviation
RSDr
2.7%
1.5%
2.2%
n/a
1.7%
8
Reproducibility limit in SMPR
≤11%
≤11%
≤11%
n/a
≤11%
9
Reproducibility relative standard deviation
RSDR
8.7%
8.8%
4.1%
n/a
5.0%
10
HorRat value
1.0
0.9
0.4
n/a
0.5
a Less than 2/9 laboratories removed from statistical analysis.
Made with FlippingBook