OMB Meeting Book_9-11-14
Table 26: Reproducibility data for whey-based infant formula test sample
Sample ID: Sample 6 W-7638/R-8320 Analyte CMP
UMP
GMP
IMP
AMP
(mg hg -1 )
(mg hg -1 )
(mg hg -1 )
(mg hg -1 )
(mg hg -1 )
Laboratory
Rep-1
Rep-2
Rep-1
Rep-2
Rep-1
Rep-2
Rep-1 0.02 a
Rep-2 0.05 a
Rep-1
Rep-2
1 2
5.17 3.94 a
5.21 3.56 a
3.60 3.26
3.60 3.11
0.99 0.70 a
1.02 1.02 a
3.68 2.58 a
3.70 3.09 a
0.00
0.00
3
5.05
4.81
2.70
3.11
1.12
1.17
0.00
0.00
3.41
3.35
4
6.20
6.00
3.60
3.80
1.10
1.10
0.00
0.00
3.70
3.70
5
6.24
6.14
3.85
3.78
1.08
1.02
0.00
0.00
3.52
3.49
6
5.47
5.41
3.83
3.87
1.05
1.05
0.00
0.00
3.43 3.63 b
3.40 3.48 b
7
5.27
5.15
3.49
3.73
0.91
1.01
0.00
0.00
8
5.36
5.41
3.69
3.60
1.05
1.06
0.00
0.00
3.36
3.39
9
5.44
5.46
3.67
3.64
1.08
1.09
0.00
0.00
3.35
3.32
10
5.63
5.60
3.60
3.61
1.08
1.06
0.00
0.00
3.73
3.72
11
5.30
5.50
3.10
3.10
1.00
1.10
0.00 0.35 a
0.00 0.24 a
3.60
3.60
12
4.80
4.83
3.78
3.89
1.02
1.04
3.30
3.43
a Identified as Grubbs outlier; results removed from data set for statistical analysis. b Identified as Cochran outlier; results kept in data set for statistical analysis.
Table 27: Reproducibility analysis for whey-based infant formula test sample
Sample ID: Sample 6 W-7638/R-8320
CMP
UMP
GMP
IMP
AMP
Analyte Symbol
Seq.
Item
Value
Value
Value
Value
Value
11 a
11 a
10 a
11 a
1 2
Total number of laboratories
n
12 24
Total number of replicates
2n
22
22
22
22
3
Overall mean of all data (grand mean)
5.43
3.54
1.05
n/a
3.51
4
Repeatability standard deviation
S r
0.09
0.11
0.04
n/a
0.05
5
Reproducibility standard deviation
S R
0.43
0.32
0.05
n/a
0.15
6
Repeatability limit in SMPR
≤6%
≤6%
≤6%
n/a
≤6%
7
Repeatability relative standard deviation
RSD r
1.6%
3.2
3.4%
n/a
1.3%
8
Reproducibility limit in SMPR
≤11%
≤11%
≤11%
n/a
≤11%
9
Reproducibility relative standard deviation
RSD R
7.9%
9.0%
5.2%
n/a
4.3%
10
HorRat value
0.9
1.0
0.5
n/a
0.5
a Less than 2/9 laboratories removed from statistical analysis.
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