OMB Meeting Book_9-11-14

Outliers (Labs removed)

Repeatability relative

Overall mean of all data (grand mean)

Repeatability standard deviation

Reproducibility standard deviation

Reproducibility relative standard deviation

Total number of laboratories

HORRAT value

Single Grubbs Test

Total number of replicates

Cochran's Test

standard deviation

13-Cis Retinyl Palmitate/Acetate as RE

Units

XBARBAR 49.4227

s(r)

s(R)

RSD(r)

RSD(R)

p

Sum(n(L))

Ppractice Sample 1 Ppractice Sample 2 EKVJ578 VJKY373 JMQT233 DQDF457 LARU224 GLVC238 ADVZ021 LUJP087 SNPZ056 CBNJ010 MNGN284 EPXW887 ZNP1092 YKLP059 MOPG098 SJLQ035 FRZK569 FHTX798

810637

4.2602 1.7461 0.0671 3.2636 0.4850 0.4843 1.4362 0.8805 0.1408 0.5518

7.4548 3.4600 0.1303 3.4367 0.5759 2.1751 2.0574 1.7236 1.2573 1.7938

8.62

15.08 21.33

0.84 1.00 0.30 1.85 0.81 0.63 1.03 0.57 1.35 0.50 1.14

Wyeth Nutri Global Control Nestle DDP 2 - 2013 P-Test

mcg/100g RTF mcg/100g RTF

15 13 15 15 15 12 15 15 14 15 15

30 26 30 30 30 24 30 30 28 30 30

DDP 2 - 2013

16.2217 1.4391 7.8940 2.5268 16.1120 13.7327 11.7489 16.9437 8.5529

10.76

1

14

mg/Kg

4.66

9.06

CLC10-b

SRM 1849a

41.34 19.20

43.54 22.79 13.50 24.06 12.55 10.70 10.59

1172572116 11750017V3 117257651Z

Infant Formula Powder Partial Hydrolyzed Milk Based mcg/100g RTF

mcg/100g RTF

Adult Nutritional Powder Milk Protein Based

2 & 3

14

3.01

Infant Formula Powder Partially Hydrolyzed Soy Based mcg/100g RTF

mcg/100g RTF mcg/100g RTF mcg/100g RTF mcg/100g RTF mcg/100g RTF

16.79

00394RF00

Adult Nutritional Powder Low Fat Infant Formula Powder Soy Based Infant Formula Powder Milk Based

6.41 1.20 3.26

E29JVLV

9

D04HTCVV

SPIFAN Milk Control

Infant Formula RTF Milk Based

3.8708

0.9107

1.1576

23.53

29.91

00403RF00

Infant Elemental Powder

Outliers (Labs removed)

Repeatability relative

Overall mean of all data (grand mean)

Repeatability standard deviation

Reproducibility standard deviation

Reproducibility relative standard deviation

Total number of laboratories

HORRAT value

Single Grubbs Test

Total number of replicates

Cochran's Test

standard deviation

Trans Retinyl Palmitate/Acetate as RE

Units

XBARBAR

s(r)

s(R)

RSD(r)

RSD(R)

p

Sum(n(L))

Ppractice Sample 1 Ppractice Sample 2 EKVJ578 VJKY373 JMQT233/DQDF457 LARU224 GLVC238 ADVZ021 LUJP087 SNPZ056 CBNJ010 MNGN284 EPXW887 ZNP1092 YKLP059 MOPG098 SJLQ035 FRZK569 FHTX798

810637

Wyeth Nutri Global Control Nestle DDP 2 - 2013 P-Test

mcg/100g RTF mcg/100g RTF

15 14 15 15 15 12 15 15 14 14 15

30 28 30 30 30 24 30 30 28 28 30

352.38 453.99

12.6081 22.0834

25.1273 48.0814

3.58 4.86 2.98

7.13

0.53 0.82 0.31 2.82 1.22 0.65 1.15 0.53 0.33 0.32 0.86

DDP 2 - 2013

14

10.59

mg/Kg

5.05

0.1506

0.3959

7.84

CLC10-b

SRM 1849a

43.35 43.23 51.28 39.00 48.83 54.83 40.30 44.48

22.3361 7.3704 1.4784 6.0814 3.7347 0.6812 0.3237 6.4568

22.3361 9.7070 6.0266 8.3122 4.6842 3.2122 2.4155 6.8880

51.52 17.05

51.52 22.45 11.75 21.32

1172572116 11750017V3 117257651Z

Infant Formula Powder Partial Hydrolyzed Milk Based mcg/100g RTF

mcg/100g RTF

Adult Nutritional Powder Milk Protein Based

2 & 3

14

2.88

Infant Formula Powder Partially Hydrolyzed Soy Based mcg/100g RTF

mcg/100g RTF mcg/100g RTF mcg/100g RTF mcg/100g RTF mcg/100g RTF

15.59

00394RF00

Adult Nutritional Powder Low Fat Infant Formula Powder Soy Based Infant Formula Powder Milk Based

7.65 1.24

9.59 5.86

E29JVLV

9 9

D04HTCVV

0.80

5.99

SPIFAN Milk Control

Infant Formula RTF Milk Based

14.52

15.49

00403RF00

Infant Elemental Powder

Outliers (Labs removed)

Repeatability relative

Overall mean of all data (grand mean)

Repeatability standard deviation

Reproducibility standard deviation

Reproducibility relative standard deviation

Total number of laboratories

HORRAT value

Single Grubbs Test

Total number of replicates

Cochran's Test

standard deviation

Total Retinyl Palmitate/Acetate as RE

Units

XBARBAR

s(r)

s(R)

RSD(r)

RSD(R)

p

Sum(n(L))

Ppractice Sample 1 Ppractice Sample 2 EKVJ578 VJKY373 JMQT233/DQDF457 LARU224 GLVC238 ADVZ021 LUJP087 SNPZ056 CBNJ010 MNGN284 EPXW887 ZNP1092 YKLP059 MOPG098 SJLQ035 FRZK569 FHTX798

810637

Wyeth Nutri Global Control Nestle DDP 2 - 2013 P-Test

mcg/100g RTF mcg/100g RTF

15 14 15 15 15 12 15 15 14 14 15

30 28 30 30 30 24 30 30 28 28 30

401.80 471.35

14.9957 22.2689

31.3624 49.5985

3.73 4.72 3.26

7.81

0.59 0.82 0.33 2.80 1.25 0.69 1.20 0.56 0.38 0.41 0.91

DDP 2 - 2013

14

10.52

mg/Kg

6.49

0.2118

0.5206

8.02

CLC10-b

SRM 1849a

51.25

25.5187

25.5187

49.80

49.80

1172572116 11750017V3 117257651Z

Infant Formula Powder Partial Hydrolyzed Milk Based mcg/100g RTF

mcg/100g RTF

46.34 67.39 47.55 62.56 66.58 57.34 48.35

7.6934 1.5484 7.5035 4.2798 0.7492 0.6089 7.3132

10.4773

16.60

22.61 11.93

Adult Nutritional Powder Milk Protein Based

2 & 3

14

8.0413

2.30

Infant Formula Powder Partially Hydrolyzed Soy Based mcg/100g RTF

mcg/100g RTF mcg/100g RTF mcg/100g RTF mcg/100g RTF mcg/100g RTF

10.3302 6.0407 4.3338 4.1275 7.8551

15.78

21.73

00394RF00

Adult Nutritional Powder Low Fat Infant Formula Powder Soy Based Infant Formula Powder Milk Based

6.84 1.13 1.06

9.66 6.51 7.20

E29JVLV

9

D04HTCVV

SPIFAN Milk Control

Infant Formula RTF Milk Based

15.13

16.25

00403RF00

Infant Elemental Powder

Outliers (Labs removed)

Repeatability relative

Overall mean of all data (grand mean)

Repeatability standard deviation

Reproducibility standard deviation

Reproducibility relative standard deviation

Total number of laboratories

HORRAT value

Single Grubbs Test

Total number of replicates

Cochran's Test

standard deviation

d: Alpha Tocopherol Acetate

Units

XBARBAR

s(r)

s(R)

RSD(r)

RSD(R)

p

Sum(n(L))

Ppractice Sample 1 Ppractice Sample 2 EKVJ578 VJKY373 JMQT233/DQDF457 LARU224 GLVC238 ADVZ021 LUJP087 SNPZ056 CBNJ010 MNGN284 EPXW887 ZNP1092 YKLP059 MOPG098 SJLQ035 FRZK569 FHTX798

810637

Wyeth Nutri Global Control Nestle DDP 2 - 2013 P-Test

mg/100g RTF mg/100g RTF

0.70 0.73 0.58 0.76 0.93 1.07 0.81 0.58 0.42 0.38 0.63

15 15 14 13 14 15 13 14 13 13 15

30 30 28 26 28 30 26 28 26 26 30

6.06 4.61

0.1489 0.1438 3.3739 0.1081 0.4888 0.0657 0.0388 0.0217 0.0206 0.0094 0.0606

0.3732 0.3048 14.9913 0.1253 0.9263 0.2025 0.1561 0.0842 0.0667 0.0648 0.1192

2.46 3.12 1.95 6.97 3.84 3.65 2.11 1.67 1.43 0.60 3.38

6.16 6.61 8.67 8.08 7.28 8.50 6.47 4.62 4.15 6.66

DDP 2 - 2013

9

mg/Kg

172.89

CLC10-b

SRM 1849a

mg/100g RTF mg/100g RTF

1.55

1172572116 11750017V3 117257651Z

Infant Formula Powder Partial Hydrolyzed Milk Based

14

12.73

Adult Nutritional Powder Milk Protein Based

1.80 1.84 1.30 1.44 1.56 1.79

11.25

Infant Formula Powder Partially Hydrolyzed Soy Based mg/100g RTF

9 9 9 9

15

mg/100g RTF mg/100g RTF mg/100g RTF mg/100g RTF mg/100g RTF

00394RF00

Adult Nutritional Powder Low Fat Infant Formula Powder Soy Based Infant Formula Powder Milk Based

E29JVLV

14 14

D04HTCVV

SPIFAN Milk Control

Infant Formula RTF Milk Based

00403RF00

Infant Elemental Powder

Outliers (Labs removed)

Repeatability relative

Overall mean of all data (grand mean)

Repeatability standard deviation

Reproducibility standard deviation

Reproducibility relative standard deviation

Total number of laboratories

HORRAT value

Single Grubbs Test

Total number of replicates

Cochran's Test

standard deviation

dL Alpha Tocopherol

Units

XBARBAR

s(r)

s(R)

RSD(r) 7.82 3.28 5.78 3.99 1.67 8.90 7.89 1.57 2.59 43.66 15.48

RSD(R)

p

Sum(n(L))

Ppractice Sample 1 Ppractice Sample 2 EKVJ578 VJKY373 JMQT233/DQDF457 LARU224 GLVC238 ADVZ021 LUJP087 SNPZ056 CBNJ010 MNGN284 EPXW887 ZNP1092 YKLP059 MOPG098 SJLQ035 FRZK569 FHTX798

810637

Wyeth Nutri Global Control Nestle DDP 2 - 2013 P-Test

mg/100g RTF mg/100g RTF

1.81 0.80 1.87 3.64 0.93 0.92 2.81 0.68 0.44 0.60 1.34

15 13 14 15 14 11 14 14 13 14 14

30 26 28 30 28 22 28 28 26 28 28

2.59 5.96

0.2027 0.1955 2.1032 0.1489 0.0230 0.0080 0.0124 0.0361 0.0077 0.0117 0.0637

0.4661 0.4178 4.5387 0.1658 0.0525 0.0569 0.0607 0.0400 0.0279 0.0350 0.0718

17.99

DDP 2 - 2013

13 & 14

7.01

14

mg/Kg

36.38

12.47 48.62

CLC10-b

SRM 1849a

mg/100g RTF mg/100g RTF

0.34 0.58 0.48 0.14 0.46 0.49 0.45 0.41

1172572116 11750017V3 117257651Z

Infant Formula Powder Partial Hydrolyzed Milk Based

14 14

9.10

Adult Nutritional Powder Milk Protein Based

1 -3

11.94 43.56

Infant Formula Powder Partially Hydrolyzed Soy Based mg/100g RTF

1

mg/100g RTF mg/100g RTF mg/100g RTF mg/100g RTF mg/100g RTF

00394RF00

Adult Nutritional Powder Low Fat Infant Formula Powder Soy Based Infant Formula Powder Milk Based

14 14 14 14

8.74 5.68 7.73

E29JVLV

9

D04HTCVV

SPIFAN Milk Control

Infant Formula RTF Milk Based

17.44

00403RF00

Infant Elemental Powder

Outliers (Labs removed)

Repeatability relative

Overall mean of all data (grand mean)

Repeatability standard deviation

Reproducibility standard deviation

Reproducibility relative standard deviation

Total number of laboratories

HORRAT value

Single Grubbs Test

Total number of replicates

Cochran's Test

standard deviation

Total Vitamin E as TE

Units

XBARBAR

s(r)

s(R)

RSD(r)

RSD(R)

p

Sum(n(L))

Ppractice Sample 1 Ppractice Sample 2 EKVJ578 VJKY373 JMQT233/DQDF457 LARU224 GLVC238 ADVZ021 LUJP087 SNPZ056 CBNJ010 MNGN284 EPXW887 ZNP1092 YKLP059 MOPG098 SJLQ035 FRZK569 FHTX798

810637

Wyeth Nutri Global Control Nestle DDP 2 - 2013 P-Test

mg/100g RTF mg/100g RTF

0.74 0.63 0.27 1.15 0.93 1.00 1.04 0.68 0.40 0.37 0.55

15 12 12 14 14 15 14 14 14 14 15

30 24 24 28 28 30 28 28 28 28 30

5.98 7.50

0.1955 0.1230 4.0620 0.1458 0.4972 0.1240 0.0528 0.0370 0.0256 0.0163 0.1046

0.3886 0.4014 8.1769 0.2246 0.9545 0.2307 0.2104 0.0754 0.0800 0.0772 0.1233

3.27 1.64 1.94 7.79 3.74 5.46 2.71 2.07 1.32 0.81 4.70

6.50 5.35 3.91

DDP 2 - 2013

8 & 13 & 14

9 9

13 & 15

mg/Kg

209.24

CLC10-b

SRM 1849a

mg/100g RTF mg/100g RTF

1.87

12.01

1172572116 11750017V3 117257651Z

Infant Formula Powder Partial Hydrolyzed Milk Based

14

13.30

7.17

Adult Nutritional Powder Milk Protein Based

2.27 1.95 1.79 1.94 2.01 2.22

10.15 10.78

Infant Formula Powder Partially Hydrolyzed Soy Based mg/100g RTF

9 9 9 9

mg/100g RTF mg/100g RTF mg/100g RTF mg/100g RTF mg/100g RTF

00394RF00

Adult Nutritional Powder Low Fat Infant Formula Powder Soy Based Infant Formula Powder Milk Based

4.22 4.13 3.84 5.55

E29JVLV

D04HTCVV

SPIFAN Milk Control

Infant Formula RTF Milk Based

00403RF00

Infant Elemental Powder