OMB Meeting Book_9-11-14

COMMENT PARAMETERS 

USER COMMENTS 

AOAC OMA 

2011.10 

Method Name/Manuscript Title 

Vitamin B12 in Infant Formula and Adult Nutritionals  High‐Performance Liquid Chromatography  J. AOAC Int. 95, 313(2012); AOAC SMPR 2011.005  J. AOAC Int. 95, 293(2012) 

Manuscript Reference 

In your experience using the method, does the  method perform according to the method’s  applicability as written?  In your experience with the method, is there  any safety concerns identified while using or  regarding use of the method?  Do you have any information that supports  regarding the reproducibility of the method as  written:  If so, please specify and submit  information?  Please attach any documentation to support  your feedback, if available.    Based on your experience with the method,  are there any recommended changes to the  AOAC First Action Method as written? 

Yes 

Fumes generated during mobile phase preparations (TEA and Formic  Acid) and fumes from oven during heating of samples (cyanide). 

None 

Include a note that the method (all preparations) should be carried  out under a fume hood and ensure that oven vent is connected to an  exhaust system.