OMB Meeting Book (June 25-26, 2015)

During its second meeting in April 2011, SPIFAN approved the first of the five SMPRs in which NIST 1 Infant formula SRM 1849. This SRM is stated as the primary reference material in all SPIFAN SMPRs. 2 The NIST SRM 1849a material was tested as part of a supplemental data set for the method and 3 reviewed by the ERP prior to the method’s adoption as AOAC 2012.15. Furthermore, during this meeting 4 the SPIFAN Working Group on SPIFAN Matrices presented a list of testing materials that would be 5 donated by the infant formula manufacturers, characterized, and stored 4 . See appendices – SPIFAN 6 product matrices and SPIFAN SLV Kit 5 . 7 8 B. Guidance and support can be obtained from the AOAC Technical Division on Reference Materials. 9 10 As part of the development of the SMPRs, AOAC has added a document from the AOAC Technical 11 Division on Reference Materials (TDRM) at the request of TDRM, to the SMPR guidelines 6 (OMA 12 Appendix F). AOAC OMB has reviewed this information prior to its publication in the OMA. 15 A. Data demonstrating Response Linearity, Accuracy, Repeatability, LOD/LOQ, and Matrix Scope must 16 be present. Experimental designs to collect this data may vary with the method protocol and the 17 intended use of the method. 18 19 The ERP reviewed three papers 7,8,9 one of which included a single laboratory validation (SLV) for AOAC 20 2012.15. This information along with the method evaluation form was then used to confirm that this 21 method would move forward towards Final Action recommendation with the inclusion of a 22 reproducibility evaluation. Additionally, the SPIFAN SLV Guidelines 10 was prepared by a group chair by 23 13 14 SINGLE LABORATORY VALIDATION: 4 AOAC SPIFAN Meeting Minutes from AOAC SPIFAN meeting held on April 5, 2011 (Day 1 of AOAC SPIFAN meeting) 5 SPIFAN Single Laboratory Validation Kit – Common infant formula reference materials. 6 Appendix F: Guidelines for Standard Method Performance Requirements Official Methods of Analysis of AOAC INTERNATIONAL e-OMA at www.aoac.org . 7 Sullivan, Darryl and Zywicki, Richard, Determination of Total Iodine in Food and Dietary Supplements Using Inductively Coupled Plasma-Mass Spectrometry Journal of AOAC INTERNATIONAL 2012, volume 95. 8 Covance Laboratories Inc. Nutritional Chemistry and Food Safety, AOAC SPIFAN Supplemental Data to IOD-2 from Iodine Analysis in Infant Formula and Adult Nutritionals Using a Covance Developed Method: “Determination of Total Iodine in Foods and Dietary Supplements using Inductively Coupled Plasma-Mass Spectrometry. Issue Date: 10 August 2012. 9 Covance Laboratories Inc. Nutritional Chemistry and Food Safety, AOAC SPIFAN Single Laboratory Validation for Iodine Analysis in Infant Formula and Adult Nutritionals, First Action 2012.15, Report Issue Date: 25 July 2013. 10 Appendix L: AOAC Recommended Guidelines for Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN) Single- Laboratory Validation ,

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