OMB Meeting Book (March 2, 2017)
OMB Meeting Book
36
Department of Pharmacology, Robert Wood Johnson Medical School-UMDNJ, Piscataway, New Jersey, USA Performed research in drug discovery and development of anti-AIDS and anti-cancer; Contributed in drug design and structural optimization, drug synthesis and characterization, purification and preformulation Conducted analytical and bioanalytical method development and validation of drug substance Performed separation, elucidation and identification of active pharmaceutical ingredient using HPLC, LC-MS/MS, MALDI-TOF MS and NMR Conducted pharmaceutical analysis of biological samples to evaluate the pharmacokinetics and elucidate the metabolite of organic drug compounds Conducted pegylation of active pharmaceutical ingredient to increase bioavailability and optimize pharmacokinetics Performed design and optimization of drug structure to increase inhibition efficacy to fight AIDS Performed preparative separation to obtain the most active species against AIDS using semi-prep and prep HPLC Mar. 2005 - July 2007 Collaboration scientist Novaflux Biosciences Inc., Princeton, New Jersey, USA Developed microbicides from homopolymer and copolymer of guanides and their derivatives (PBGs) to prevent HIV-AIDS transmission Performed preformulation of topical microbicides as the fusion inhibitor of HIV type-1 virus Investigated the feasible applications of PBGs on other infectious diseases Conducted the characterization and identification of active pharmaceutical ingredient and drug substance by NMR, HPLC, LC-MS/MS and MALDI-TOF MS Sep.1999 - Dec. 2004 Research and Teaching Assistant Department of Chemistry and Biochemistry, Auburn University, Auburn, AL Conducted qualitative and quantitative analytical method development and validation with HPLC, HPAEC, IEC, LC-MS, GC-IR, GC-MS, ESI-MS and MALDI-TOF MS Developed electroactive polymers and completed characterization of their chemical and physical properties by various techniques Performed isolation and identification of biological samples including proteins, peptides and saccharides Developed a group of gas sensors with high selectivity and sensitivity for volatile organic compounds (VOCs) Discovered the polymerization and redox switching mechanism using electrochemistry combined with Electrochemical Quartz Crystal Microgravity Instructed Instrumental Analysis Lab, Chemical Analysis Lab and General Chemistry Lab; Supervised and trained graduate and undergraduate students July 1993 - Aug. 1999 Process Engineer SINOPEC Shanghai Engineering Company Limited (SSEC), Shanghai, P.R.China Conducted process evaluation and improvement, transferred manufacturing process from R&D to operations Developed and designed process flow, plant layout, equipment and piping system Committed ANSI, API, cGMP and FDA requirement for chemical and pharmaceutical industries Conducted and evaluated on-site installation, troubleshooting, validation, start-up and commission run test
China Petrolum & Chemical Corporation Former Shanghai Pharmaceutical Industry Design Institute (SPIDI)
March 2, 2017
Made with FlippingBook