Review Team (February 2016)

AOAC SMPR 2015.003

Table 1. Method performance requirements a Analytical range

30–4000 b

Limit of quantitation (LOQ)

”

b

Standard Method Performance Requirements SM (SMPRs) for Total Vitamin B 2 5LERÀDYLQ LQ ,QIDQW and Adult/ Pediatric Nutritional Formula

Recovery

90–110%

Repeatability (RSD r ) Reproducibility (RSD R )

”

” a Concentrations apply to: (a) “ready-to-feed” liquids “as is”; (b) reconstituted powders (25 g into 200 g water); and (c) liquid concentrates diluted 1:1 by weight. b ȝJ J UHFRQVWLWXWHG ¿QDO SURGXFW

Intended Use: Reference Method for Dispute Resolution

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5 System Suitability Tests and/or Analytical Quality Control 6XLWDEOH PHWKRGV ZLOO LQFOXGH EODQN FKHFN VDPSOHV DQG FKHFN VWDQGDUGV DW WKH ORZHVW SRLQW DQG PLGUDQJH SRLQW RI WKH DQDO\WLFDO UDQJH 6 Reference Material(s) 1,67 6WDQGDUG 5HIHUHQFH 0DWHULDO ® 650 D ,QIDQW $GXOW 1XWULWLRQDO )RUPXOD RU HTXLYDOHQW 7KH 650 LV D PLON EDVHG K\EULG infant/adult nutritional powder prepared by a manufacturer of LQIDQW IRUPXOD DQG DGXOW QXWULWLRQDO SURGXFWV $ XQLW RI 650 FRQVLVWV RI SDFNHWV HDFK FRQWDLQLQJ DSSUR[LPDWHO\ J RI PDWHULDO &HUWL¿HG YDOXH RI 1,67 D LV “ PJ NJ ULERÀDYLQ 7 Validation Guidance 5HFRPPHQGHG OHYHO RI YDOLGDWLRQ 2I¿FLDO 0HWKRGV RI $QDO\VLV SM 8 Maximum Time-to-Result 1R PD[LPXP WLPH Approved by AOAC Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN). Final Version Date: April 17, 2015. Effective Date: April 17, 2015.

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