SPADA Book - April 11, 2017

Optional Bioinformatics

• Instructions for application of bioinformatics analysis were  developed for the Variola and Fransicella standards

• These instruction were refined and added as an option to  wet testing of Group 2 organisms (cultivatable soil, water,  and air bacteria)

• Only DNA from Group 1 are recommended for evaluation  regardless of bioinformatics analysis

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Streamlined EOP

• Number of species DNA required for wet testing: reduced from 86 to 49 species (reduced by 43%)

• Number of species DNA required for wet testing  in  tandem with bioinformatic analysis: reduced from 86 to 12 species (reduced by 86%)

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