SPADA at AOAC Annual Meeting 2023
‘RUMSFELDISM’ IN NGS APPLICATIONS
Donald Rumsfeld in a press briefing back in 2002 introduced the concept with respect to threats facing the country
Known Pathogen Unknown Target Usual suspects plus (SARS-CoV-2 variants) • Targeted AmpSeq • Isolate sequencing
Known Pathogen Known Target Usual suspects • Real time PCR • Targeted AmpSeq
Unknown Pathogen
Unknown Pathogen Known Target Newly
Unknown Target One that defies logic (Discovery) • MetaSeq • Isolate sequencing
emergent/engineered with usual attributes ( B. cereus var. anthracis ” CI) • Targeted AmpSeq (16S) • Isolate sequencing
Solving for complexity Posted on January 26, 2021 by Doug Belshaw
UNCLASSIFIED
10
AOAC Annual 2023
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