SPADA
Sequenced near neighbors
Whole genome SNP phylogeny of Francisella by the Swedish Defense Research Agency (FOI)
SMPR Key Points
• In silico screening required – Purpose: Predict specificity and inclusivity across all sequenced Francisella strains – Approach: Use Basic Alignment Search Tool (BLAST) to predict hybridization events between signatures components (e.g., oligo primers/probes/amplicons) and available Francisella genomic sequences in GenBank – Include results of in silico analyses in method/ assay performance evaluation reports
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