SPDS 09052014

Adulteration of Dietary Supplements  with Synthetic PDE5 Inhibitors

• Serious problem – Potential serious adverse (even lethal) health affects – Adulteration with approved drugs but also their  unapproved analogs (unknown toxicological effects) – High incidence of adulteration

Campbell et al ., J. Sex. Med. 10 (2013) 1842‐1849: ‐ 81% out of 91 tested herbal products adulterated  with synthetic PDE5 inhibitors and their analogs

Adulteration of Dietary Supplements  with Synthetic PDE5 Inhibitors

77% of the products contained synthetic drugs and their analogs