SPDS ERP Review-May 2015

Martha L. Jennens Covance Laboratories (608) 210-7781 martha.jennens@covance.com

PROFESSIONAL EXPERIENCE

2013-present Research Chemist II. This role is within the Technical Development group and serves Nutritional Chemisty as a whole as a technical resource. Perform client specific methods as needed and develop methods for new analysis. Utilize new instrumentation including LC/MS/MS. Support the Technical Development group’s IT needs by putting assays into our Labware Documentation System as well as helping trouble-shoot the current assays in the system. 2009-2013 Technical Leader III-Covance Laboratories. Oversee the technical conduct for routine and study work in the Special Analysis group. Work on method development and validation within the group to update or develop new assays for the group. Review data and communicate information or questions to the client service staff and external clients as needed. Also, complete OOS investigations and respond to QA audits as needed. Provide back- up technical leader assistance to other groups as needed and trained technical leaders at the Singapore facility. 2007-2009 Research Assistant III-Covance Laboratories. Provide troubleshooting, root cause analysis, and process validation expertise to multiple project areas. Work on method development/validation for client specific studies and new methods. Conduct stability studies and routine assays, including work with HPLC, GC and LCMS under GLP guidelines. Multi-departmental assay assistance across three separate groups, as needed. Travel to other sites to provide support of methods and data management and continue to provide support to other sites as issues arise. Provide final review of data before submission to clients. Discuss issues and projects with clients as they arise and work to resolve data/testing issues. 2005-2007 Research Assistant-UW Madison. Immunology research including RNA, cDNA and qPCR work. Cell culture of mammalian cell lines and viral transfection and transductions. DNA work including cloning and purification. Maintained laboratory supplies and trained undergraduate students.

2004-2005 Scientist/ Project Manager-PPD Development. HPLC, CGE testing in cGMP environment of pharmaceutical compounds. Project manager--responsible for overseeing project, data and report writing.

2003-2004 Laboratory Manager/ Research Assistant-University of Wisconsin, Madison. RT-PCR, cell culture, cell staining techniques, ordering and maintenance of laboratory supplies and equipment, oversee graduate students and give technical advice.

1997-2002 Scientist-Promega Corporation. Production of restriction enzymes utilizing various chromatography techniques. Product development and process improvement, feasibility issues for new technology, new product launches including packaging validation, writing manufacturing and QC protocols as well as SOPs. Understand and work with the ISO 9000 quality system. Tissue culture work-establishing stable cell lines, maintenance of several mammalian cell lines, electroporation methods. Protein purification-purifying proteins from bacterial cells, FPLC use Millennium software with Waters system, HPLC with HP Aligent system, characterization and kinetics of purified proteins. Served as hot lab supervisor for multiple group use lab. Product affiliations: IsoQuant, Steady- Glo, DLR 1000, thermostable luciferase. 1995-1997 Research Assistant-Agracetus/ Powderject, Inc. Working on DNA vaccines with Accell technology, specifically tropical and exotic diseases. Duties include: cloning, DNA sequencing, SDS PAGE analysis, tissue culture with several mammalian cell lines, RNA work, ELISAs, animal work, CTL assays, analyze and compile data with various computer software, upkeep of accurate notebooks, working with collaborating labs and served on radiation safety committee.