SPDS Lutein and Turmeric ERPs

General Information

Reviewer Name:

Melissa Phillips

Email:

melissa.phillips@nist.gov

Organization:

NIST

Method Reviewed:

TUR‐01

Method Title:

Curcuminoids in Turmeric Roots and Supplements:  Method Optimization and  Validation

Applicable SMPR

2016.003

I.  Summary

Summary of Method:

A methanol extraction followed by LC‐absorbance for determination of CUR, BDMC,  and DMC in turmeric materials.  A full method validation is described including  optimization of multiple experimental conditions.

1.  Does the Applicability of the  Method Support the Applicability  of the SMPR?  If not, please explain  what is missing. II.  Review of the Method Only 2.  Does the analytical technique(s)  used in the method meet the  SMPR?  If not, please specify how it  differs from what is stated in the  SMPR. 3.  Are the definitions specified in  the SMPR used and applied  appropriatly in the method?  If no,  please indicate how the terms are  used. 4.  Does the method, as written,  contain all appropriate precautions  and warnings related to the  method's regaents, components,  instrumentation, or method steps  that may be hazardous?  If no,  please suggest wording or  option(s). 1.  Are the definitions specified in  the SMPR used and applied  appropriately in the supporting  documentation (manuscripts,  method studies, etc…)?  If not,  please explain the differences and  if the method is impacted by the  difference.  

Yes

Yes

Yes

No safety information is included.  Could potentially include a statement regarding  flammability of solvents, acidity of mobile phase, as well as use of elevated column  temperature, but this is not critical.

III.  Review of Information in Support of the Method

Yes