SPDS eBook March 2017

Stakeholder Panel on Dietary Supplements: Background and Fitness for Purpose for SAMe

Joseph Zhou, Ph.D. Sunshineville Health Products, Inc AOAC Meeting Gaithersburg, Maryland March 17, 2017

Background on SAMe ▪ SAMe Full Name: S-Adenosyl-L-Methionine; Other Name: SAMe, SAM-e, or SAM; ▪ One of the most popular dietary supplements; ▪ Popular Product Format: Tablets in Blister Pack;

Dosage: 200mg-400mg/Tablet, 2-4 Tablets daily;

▪ Principal Structure Function: Methyl Donor ▪ Medical Uses: Depression, Osteoarthritis