SPDS eBook March 2017

G UIDELINES FOR S TANDARD M ETHOD P ERFORMANCE R EQUIREMENTS

AOAC O FFICIAL M ETHODS OF A NALYSIS (2012)

Appendix F, p. 6

Table A1. Performance requirements

Classifications of methods a

Quantitative method

Qualitative method

Main component b

Trace or contaminant c

Main component b

Trace or contaminant c

Identification method

Parameter

Single-laboratory validation

Applicable range

Applicable range

Inclusivity/selectivity

Inclusivity/selectivity

Inclusivity/selectivity

Bias d

Bias d

Exclusivity/cross-reactivity

Exclusivity/cross-reactivity

Exclusivity/cross-reactivity

Precision

Precision

Environmental interference

Environmental interference

Environmental interference

Recovery

Recovery

Laboratory variance

Laboratory variance

Limit of quantitation (LOQ)

LOQ

POD at AMDL f

Probability of detection (POD) e

Probability of identification (POI)

Reproducibility

RSD or target measurement uncertainty R

RSD or target measurement uncertainty R

POD (0)

POD (0)

POI (c)

POD (c)

POD (c)

Laboratory POD g

Laboratory POD g

Laboratory POI

a See Annex B for additional information on classification of methods. b ≥ 100 g/kg. c <100 g/kg. d If a reference material is available. e At a critical level. f AMDL = Acceptable minimum detection level. g LPOD = CPOD.

© 2012 AOAC INTERNATIONAL