SPDS eBook March 2017

Background

• Ginger rhizome is a widespread medicinal herb,  both in the eastern and western medical traditions • The constituents that the medicinal properties  have been historically ascribed to are gingerols and  shogaols ; more recently, also paradols ; collectively  referred to as pungent principles.  Quantitation of  gingerdiols and  gingerdiones is also conducted. • Ginger is most commonly employed as an anti‐ emetic, anti‐dyspeptic, anti‐inflammatory,  carminative, anti‐thrombotic

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anb@usp.org

03/17/2017

Background

• Ginger in pharmacopoeial monographs – EP, BP: content of essential oil – JP (17 Ed.): [6]‐gingerol and [6]‐shogaol only for ID (TLC) – KP X: [6]‐gingerol for ID (TLC) and assay (LC‐UV) – ChP 2015: [6]‐gingerol  for ID (TLC) and assay (LC‐UV) – USP 39: [6]‐gingerol and [6]‐shogaol for ID (HPTLC) gingerols and gingerdiones (LC‐UV) gingerols, shogaols and gingerdiones (LC‐UV) 

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anb@usp.org

03/17/2017