SPIFAN Nutrients ERP Info to OMB
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EXPERT REVIEW PANEL Stakeholder Program on Infant Formula and Adult Nutritionals (SPIFAN) DOCUMENTS REVIEW
November 18, 2022
AOAC INTERNATIONAL 2275 Research Blvd. Ste. 300 Rockville, MD, 20850 UNITED STATES
dboyd@aoac.org 301.924.7077 x12
MEMORANDUM
DATE:
November 9, 2022
TO:
AOAC Official Methods Board (OMB)
FROM: Delia Boyd, Senior Manager SUBJECT: AOAC SPIFAN Nutrients Expert Review Panel (ERP)
Background: In accordance with the policy for Official First Action, an expert review panel is being assembled to review methods submitted into the AOAC SPIFAN process for priority nutrients. AOAC staff has collected CVs and they are on file at AOAC in accordance with the revised ERP policiesand procedures. A proposal for the AOAC SPIFAN Expert Review Panel is submitted for your consideration.
The attached package contains the following information: CVs for all proposed candidate(s)
List of Expert Review Panel (ERP) members Balance of Perspectives CVs
This expert review panel operates under AOAC policies and procedures. Each expert is required to sign the AOAC Volunteer Acceptance Form which includes adherence to the AOAC policy for Volunteer Conflict of Interest, Antitrust and Use of Association Name, Letterhead and Logo. These documents will be enforced by the Expert Review Panel chair and facilitated by AOAC staff. We request the OMB to review and confirm the expertise of proposed candidates also reviewing the balance of the panel as well as the conflicts of interest of proposed members. This Expert Review Panel is scheduled to meet “Virtually” on December 7, 2022. Your review and approval of the panel is requested. Please address questions regarding the attached package to me and thank you for your consideration. Recommendation: To remove name(s) for vetting SPIFAN Nutrients Expert Review Panel (ERP)
1. Esther Campos-Gimenez
Société des Produits Nestlé
Removal
To add name(s) for vetting SPIFAN Nutrients Expert Review Panel (ERP)
2. Christophe Fuerer
Société des Produits Nestlé
Addition
AOAC INTERNATIONAL Stakeholder Panel on Infant Formula & Adult Nutritionals (SPIFAN) Nutrients Expert Review Panels (ERP) November 9, 2022 NUTRIENT PANEL 1. Darryl Sullivan (ERP Chair) Eurofins US 2. Sean Austin (FOS/GOS Only) Christophe Fuerer Société des Produits Nestlé 3. Sneh Bhandari Independent Consultant 4. Hans Cruijsen/Martine van Gool FrieslandCampina 5. Brendon Gill Fonterra Cooperative 6. Karen Schimpf/Philip Haselberger (HMO Only) Abbott Nutrition 7. Estela Kneeteman INTI 8. Maria Ofitserova Pickering Labs 9. Thomas Vennard/Shay Phillips Reckitt 10. Melissa Phillips/Kate Rimmer NIST 11. Yannis Vrasidas (HMO Only) Consultant 12. David Woollard Independent Consultant 13. Jinchuan Yang Waters Corporation
Christophe Fuerer , PhD Société des Produits Nestlé SA
Nestlé Research Route du Jorat 57 1000 Lausanne 26 Switzerland +41 21 785 80 16 christophe.fuerer@rdls.nestle.com Experience Société des Produits Nestlé SA , Nestlé Research , Switzerland
06/2014 – present Senior Specialist (2018-present) Proteins Analysis , mass spectrometry, analytical chemistry & Proteins Specialist (2014-2018) Proteins Analysis , mass spectrometry, analytical chemistry & Proteins Manage the Nestlé portfolio of analytical protein methods, evaluate proficiency tests, develop and validate analytical methods, liaise with standardization bodies, provide expert assistance to quality assurance centers, R&D centers, and factories, supervise lab technicians, and coordinate lab work Mass Spectrometry Intact protein analyses (proteoform fingerprinting and quantification) by UHPLC-HRMS, with an emphasis on the detection of genetic variants and protein glycation Multiple Reaction Monitoring (MRM) methods for absolute quantification of trace allergens in food matrices and milk proteins in dairy matrices Method development and validation Intact protein fingerprinting, detection, and quantification of milk proteins by UHPLC-HRMS Amino acids in food matrices by UHPLC-UV Whey protein content by capillary gel electrophoresis Trace amounts of intact proteins by gel electrophoresis Method standardization and active contribution to standardization bodies AOAC International Total Amino Acids by UHPLC-UV (Final Action 2018.06, author) Whey protein content in infant formula by SDS-CGE (Final Action 2016.15, author) A1- and A2-type beta casein (accepted SMPR, working group member) Lactoferrin (SMPR 2020.005, working group member) Food allergens by MS (SMPR 2016.002, working group member) IDF/ISO Total Amino Acids by UHPLC-UV (DIS in discussion, author) Whey protein content by SDS-CGE (IDF 247, ISO 23293, author) Evaluation of nitrogen conversion factors (IDF Bulletin, co-author) USP Detection of foreign proteins in whey (FCC, Appendix XVI, author) Revision of whey monographs with focus on authenticity (expert panel member) CEN Protein and amino acid analyses in algae (TC454/WG7 - Algae and algae products, Product test methods - saccharides, proteins, amino-acids, panel member)
EPFL (Ecole Polytechnique Fédérale de Lausanne) , Switzerland
01/2009 – 05/2014
Research Associate , biochemistry, cellular biology & mass spectrometry Developed a quantitative LC-MS/MS analytical assay for early markers of Alzheimer’s disease Developed growth factors purification workflows and companion analytical assays
Stanford University , California, USA
04/2005 – 11/2008
Research Associate , cellular biology, stem cells, biochemistry Purified and stabilized bioactive growth factors prone to aggregation Generated lentiviral vectors (1000+ vectors distributed worldwide)
ISREC (Institut Suisse de Recherche Expérimentale sur le Cancer) , Switzerland
11/1999 – 12/2004
PhD student and Postdoctoral fellow , oncology, viral therapy Created complex replicating oncolytic adenoviruses
Expertise
Mass spectrometry:
Intact protein analyses by UHPLC-HRMS, absolute protein quantification by Parallel and Multiple Reaction Monitoring (PRM/MRM), peptide profiling by LC-MS/MS
Separation techniques: HPLC/UHPLC, capillary gel electrophoresis, gel electrophoresis Biology/biochemistry: bioactive protein purification, reporter assay development, stable cell line generation Virology: lentiviruses, replicating adenoviruses Education
Ph.D. (Life Sciences), Université de Lausanne , Faculté de Biologie et de Médecine
2004 1999
M.Sc. ( Biochemistry), Université de Genève , Faculté des Sciences
Continuous education
Project management fundamentals
Nestlé, Lausanne, 2018
Intent-based leadership
Turn the Ship Around, LLC. Lausanne, 2016
Method validation
Nestlé, Lausanne, 2015
Business plan and Startup development
Venture Challenge, CTI, Lausanne, 2013-2014
Safety coordinator
SUVA, Lausanne, 2012
Societies
CEN (European Committee for Standardization, panel member) USP (United States Pharmacopeia, expert panel member)
since 2022 since 2018 since 2018 since 2016 since 2015 since 2014 since 2000
SNV (Schweizerische Normen-Vereinigung, subcommittee on Milk and milk products, member)
AOAC International (method author, SMPR working groups) IDF (International Dairy Federation, SCAMC, Action team, Task force)
SGMS (Swiss Group for Mass Spectrometry) LS2 (Life Sciences Switzerland, formerly USGEB)
Languages
English C2 German B1+
Intensive B1+ course, Wessex Academy, Lausanne, 2013
French
Mother tongue
Selected publications
(complete list at http://tinyurl.com/cfuererpub)
2020 Protein Fingerprinting and Quantification of β-Casein Variants by Ultra-Performance Liquid Chromatography High-Resolution Mass Spectrometry , Fuerer C, Jenni R, Cardinaux L, Andetsion F, Wagnière S, Moulin J, Affolter M, J Dairy Sci, 103(2):1193-1207 2019 Total Amino Acids by UHPLC-UV in Infant Formulas and Adult Nutritionals, First Action 2018.06 , Jaudzems G, Guthrie J, Lahrichi S, Fuerer C, J AOAC Int, 102(5):1574-1588 2018 Quantification of Whey Protein Content in Milk-Based Infant Formula Powders by Sodium Dodecyl Sulfate – Capillary Gel Electrophoresis (SDS-CGE): Multi-Laboratory Testing Study, Final Action 2016.15 , Feng P, Fuerer C, McMahon A, J AOAC Int, 101(5):1566-1577 2017 Quantification of Whey Protein Content in Infant Formulas by Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis (SDS-CGE): Single-Laboratory Validation, First Action 2016. 15, Feng P, Fuerer C, McMahon A, J AOAC Int, 100(2):510-521
AOAC INTERNATIONAL STAKEHOLDER PROGRAM ON INFANT FORMULA & ADULT NUTRITIONALS (SPIFAN) Nutrients Expert Review Panel (BALANCE OF REGION/PERSPECTIVE) _________________________________________________
ERP Members by Region
ERP Members by Perspective
AOAC SPIFAN Nutrients ERP Members by Perspective
Academia 0%
CRO 12%
Government 18%
Academia CRO Government Industry
Industry 70%
AOAC OFFICIAL METHODS BOARD (OMB) Review of AOAC SPIFAN Members e-Ballot November 9, 2022
Click here to complete the form or copy link below into browser https://form.jotform.com/223148818917162
Deadline date is December 5, 2022
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