SPSFAM Meeting eBook March 2017

3/9/2017

SMPR Key Points

Concentrates

Dried Plant Material

Requirement  (Additional,  Desirable  Cannabinoids  (Table 1b),  including CBN)

Requirement (Pertains to Cannabinoids  in Table 1b)

Parameter

Requirement  THC, THCA, CBDA, CBD,  Individually Reported

Parameter

Limit of Quantitation (LOQ)  (%)

≤ 0.1

Limit of  Quantitation (LOQ)   (% w/w)

≤ 0.3

≤ 0.3

Analytical Range (%)

0.1 – ca. 50*

Analytical Range  (% w/w)

≤ 0.3 – ca. 100

≤ 0.3 – ca. 50

*Lower concentrations may be acceptable as applicable for  cannabinoids listed in Table 1B.

Ranges (%) (Pertains to Cannabinoids in Table 1b)

Ranges (% w/w)

Parameters

Parameters

≤ 0.3 – 1

> 1 ‐ 10 > 10 – ca.  100

0.1 – 1

> 1 ‐ 25 > 25 – ca. 50

95 – 105

97 ‐ 103 98 ‐ 102

Recovery (% w/w)

Recovery (%)

95 – 105

97 ‐ 103

98 ‐ 102

≤ 5

≤ 4

≤ 2

% RSD r

% RSD r

≤ 5

≤ 4

≤ 2

≤ 7

≤ 5

≤ 3

% RSD R

% RSD R

≤ 7

≤ 5

≤ 3

Comments Submitted

5 Comments were received for SMPR –dried  materials. 1. The proposed procedures should add (a)  Instrument Detection Limit (IDL), and (b)  Method Detection Limit (MDL)  Action: WG decided to use LOD which is the  equivalent of IDL, which uses blank matrix  samples;  LOD uses matrix samples.  MDL was  purposefully removed by the WG.

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