SPSFAM EXPERT REVIEW PANEL

AOAC SPSFAM ERP REVIEW: MAIN FORM

Submission Date

2017-09-16 22:05:30

Name

Mehmet Gumustas

E-mail

mgumustas@hotmail.com

Organization

Ankara University

Title of Method

Determination of free Bisphenol A in commercially packaged ready to consume carbonated/non-carbonated water and beverages by ımmunoaffinity purification and HPLC fluorescent detection

AOAC Candidate Method Number (e.g. ALN-01)

#BPA-02

Applicable SMPR

Bisphenol-A (BPA)

I. Summary of the Method

This is a immunoaffinity purification following HPLC with FL detection method for the determination of free Bisphenol A in commercially packaged carbonated and non carbonated water, as well as non-alcoholic beverages. The method protocol calls for following different sample preparation techniques for carbonated and non carbonated water and other type of samples. After the preparation of samples the analysis has been done by using HPLC with FL detector. From the view point of HPLC system suitability test results were not mentioned. Also the stress degradation studies needs to be added for demonstrating the specificity of the developed method.

II. Review of the Method Only 1. Does the applicability of the method support the applicability of the SMPR? If not, please explain what is missing. 2. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify how it differs from what is stated in the SMPR. 3. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used.

Applicability of the developed method support the SMPR

The chosen analytical technique (HPLC-FL) meet the SMPR

All mentioned definitions specified in the SMP used and applied appropriately