SPSFAM EXPERT REVIEW PANEL

3. Is there information demonstrating that the method system suitability tests and controls as specified in the SMPR worked appropriately and as expected? If no, please specify. 4. Based on the supporting information, is the method written clearly and concisely? If no, please specify the needed revisions. 5. Based on the supporting information, what are the pros/strengths of the method?

YES

YES

1.Sample preparation is simple and cost effective. 2.. Method Specificity well established as per EC decision 2002/657/EC. 3. To achieve high recoveries developer used labelled internal standards .

Method is most accurate and confirmatory.

Method clearly covered and stated all the parameters mentioned in AOAC BPA SMPR .

6. Based on the supporting information, what are the cons/weaknesses of the method?

May be require to perform recovery at 2 to 5 ug/L to cover entire analytical ranges as mentioned in BPA SMPR.

7. Any general comments about the method?

NO

V. Final Recommendation Do you recommend this method be adopted as a First Action and published in the Official Methods of Analysis of AOAC INTERNATIONAL? Please specify rationale.

YES