SPSFAM EXPERT REVIEW PANEL

AOAC SPDS ERP REVIEW: MAIN FORM

Submission Date

2017-09-14 22:42:09

Name

Jing Tan

E-mail

jtan@abbott.com

Organization

Abbott Nutrition R&D

Title of Method

Immunoaffinity purification and HPLC fluorescent detection

AOAC Candidate Method Number (e.g. ALN-01)

BPA-02

Applicable SMPR

BPA_SMPR_V6

Summary:

In this method, immunoaffinity column (IAC) was used for sample cleanup and concentrating, and BPA was determined by HPLC-FLD. It is of high specificity. The method is relatively easy to implement in term of sample preparation and instrument operation and maintenance. Authors have demonstrated most of the method performance according to the definitions in SMPR. But additional information is needed on system suitability and analytical quality control.

1. Does the applicability of the method support the applicability of the SMPR? If not, please explain what is missing. 2. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify how it differs from what is stated in the SMPR. 3. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used. 4. Does the method, as written, contain all appropriate precautions and warnings related to the method's reagents, components, instrumentation, or method steps that may be hazardous? If no, please suggest wording or option(s).

Yes

Yes

Yes

There is no precaution or warnings written in the method.