Stakeholder Panel Meeting Book - September 6, 2014
B 3 Forms, Chemistry, and Stability i i i id i h i ll idi 3 b li N cot n c ac s c em ca y pyr ne ‐car oxy c acid, and nicotinamide is pyridine 3‐carboxcylic acid amide. In unprocessed foods niacin is mostly present in the form of the pyridine coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) Nicotinamide is considerably more water soluble than nicotinic acid and therefore the general choice for fortification in liquid products.
Nicotinic acid is a powerful vasodilator which can be used to lower serum cholesterol. Both free forms of B 3 have an absorbance maximum at 260nm and do not fluoresce. Niacin is the most stable water soluble d ff d b h l h vitamin, an is not a ecte y eat, ig t, acid alkali, or oxidation. Acid or alkali hydrolysis free the niacin from coenzyme structures.
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