Stakeholder Panel Meeting Book - September 6, 2014
Analytical Challenges Low levels of some inherent forms of vitamins such as nicotinic acid and Pyridoxamine. Assuring that the extraction procedure is adequate for total vitamin content. Stability! Assuring lab conditions are adequate for the testing of labile nutrients such as Riboflavin.
Future Direction or Is LC/MS the Panacea of WSV testing? WSVs are generally a natural fit for MS ionization. Internal standards are available for almost all WSVs. MS solves several detection issues with some WSVs such as Thiamine and Niacin. However you do still need considerable sample prep in certain cases to get total vitamin content. Many HPLC techniques can be very reliable, precise, accurate, and potentially less complicated to perform.
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