Stakeholder Panel Meeting Book - September 6, 2014

STAKEHOLDER PANEL ON INFANT FORMULA AND ADULT NUTRITIONALS (SPIFAN)

Ping Feng, Consultant SPIFAN Working Group Co-Chair, Amino Acids

Ms. Ping Feng joined Wyeth Nutrition as a Biochemist in 1991. Since then, she has contributed to several infant formula protein innovations including first age products with hydrolyzed protein, soy protein, and whey protein with enriched alpha-lactalbumin. Each of these innovations was supported by the development

and validation of methods for amino acid analysis, individual intact protein quantification and molecular weight profile determination. In preparation for product launches, she transferred analytical assays to Quality labs of the lead manufacturing site. In 2006, Ms. Feng was appointed as manager of the protein analytical lab and in this role, provided managerial and technical leadership. Her bilingual skills in English and Mandarin have also been instrumental in the technical support she provides to Quality and Regulatory teams in China. Ms. Feng’s laboratory expertise includes proficiency with HPLC, UPLC, and all aspects of protein and amino acid analysis in infant formula matrix and biological samples. Her methods for alpha-lactalbumin using gel permeation chromatography and amino acids using UPLC have been presented at AOAC. Her 9- country human milk amino acid composition results have been presented at Experimental Biology. In August 2013, Ms. Feng was awarded 2013 Single Laboratory Validation Study of the Year by AOAC for the study entitled : AOAC Official Method 2012.08 Whey Protein Content in Milk-Based Infant Formula Finished Products Using Amino Acids Calculation Method. The related method was published at Journal of AOAC International (2013) 98, 4, 795-797. After leaving Wyeth Nutrition in June 2013 due to the lab closing, Ms. Feng currently works as a consultant for analytical method validation following ICH guidelines at Alcon/Novartis in Fort Worth, TX. Prior to joining Wyeth, Ms. Feng worked as a project liaison in Ministry of Petroleum Industry of China and a chemical engineer in the environmental industry. Ms. Feng graduated from Beijing Institute of Technology with a BSc in 1982 in Chemical Engineering and a MS from West Chester University in 1990 in Analytical Chemistry. She also completed course work for Drug Development in QA/RA and obtained a Certificate from Temple University. Dr. Jacobs is a Principal Research Scientist with Abbott Nutrition and has over 30 years of experience with analytical instrumentation, bio-analytical methods, and nutrient analysis. After completing his Ph.D. at Purdue University he spent several years working for a small manufacturer of laboratory instrumentation, in a variety of roles, but with emphasis on applications development and technical support to end users. After moving to Abbott, he was initially responsible for managing a small group focused on clinical analysis but is now focused almost entirely on supporting product development, as well as commercial manufacturing operations, through the development and implementation of appropriate analytical methods, design of data collection strategies, and analysis/interpretation of data. He has been and continues to be, involved in a variety of nutrient areas including amino acids, carbohydrates (sugars, fiber, and oligosaccharides), water soluble vitamins, carnitine, choline, and inositol. He currently leads a small group of experienced scientists covering a wide range of applications. Wesley Jacobs, Abbott Nutrition SPIFAN Working Group Co-Chair, Amino Acids