Statistics Meeting Book (February 20, 2019)

• Reference value • Repeatability (Reproducibility) • Repeatability conditions • Repeatability (Reproducibility) limit

• Repeatability (Reproducibility) standard deviation • Repeatability (Reproducibility relative standard deviation • Reproducibility conditions • Result • Robustness (ruggedness)

• Selectivity • Sensitivity • Surrogate • Systematic error • Trueness • True value • Validated range

• Validated Test Method • Validation Verification

DEFINITIONS OF ANALYTICAL TERMS Accuracy: The closeness of agreement between a test result or measurement result and a reference value. Notes: The term “accuracy,” when applied to a set of test results or measurement results, involves a combination of random components and a common systematic error or bias component. When applied to a test method, the term accuracy refers to a combination of trueness and precision. Reference: ISO Standard 3534-2: Vocabulary and Symbols Part 2: Applied Statistics, ISO, Geneva, 2006 Analyte : The chemical substance sought or determined in a sample. Note: This definition does not apply to molecular biological analytical methods. Reference: Codex Guidelines on Good Laboratory Practice in Residue Analysis (CAC/GL 40-1993)