Statistics Meeting Book (February 20, 2019)

AOAC INTERNATIONAL COMMITTEE ON STATISTICS Draft Meeting Agenda Wednesday, February 20, 2019 Meeting Start Time: 10:30 AM (Eastern US) Chair: Sidney Sudberg (Alkemist Labs) ______________________________________________________________________________ ( Need member to volunteer to take the minutes ) II. REVIEW OF MEETING AGENDA & MINUTES (All – 10:40AM-10:45AM) * The members of the Statistics Committee will review and vote on the October 16, 2018 meeting minutes and the, February 20, 2018 meeting agenda. III. CURRENT METHOD CONFORMITY ASSESSMENT PROJECTS (All– 10:45AM-11:05AM) Progress updates a. Statistics for Microbiology Methods Validation - Paul Wehling & Robert LaBudde (Leads) 1. Word copies of the Annexes for Appendix J, provided, to be able to work with equations easily: a. Robert LaBudde b. Paul Wehling I. WELCOME & INTRODUCTION (Sudberg – 10:30AM‐10:40AM) * Sidney Sudberg will call the meeting to order, welcome and introduce the members of Statistics Committee. Members will review the AOAC policy documents and vote on the draft meeting agenda.

Volunteers to check equations modified by Paul: 1. Qian Graves 2. Jane Weitzel

3. Hilde Skår Norli 4. Sidney Sudberg

b. Changes to Appendix J (in progress) - Paul Wehling & Robert LaBudde (Leads) 1. ISPAM being ‘reactivated’ to discuss: 2. Quantitative methods need changes (performed during &/or after validation) a. Candidate minus Reference b. New method of calculating the CI for the paired dPod c. Use of Z (n) vs. t (n-1) d. Removal of reference to Welch/Satterthwaite t-test? e. Chi-Square Test Calculator (Robert/Paul) http://lcfltd.com/AOAC/aoac-binary-v2-5.xlsx i. To be discussed with Appendix J changes c. Statistics Committee’s Terms of Reference (ToR) Update – All, ToR Subcommittee 1. Latest version – v8 has been approved by OMB a. Board of Directors to vote via e-Ballot,?

*Requires a vote

version 1

Draft meeting agenda is subject to change without notice