Statistics Meeting Book (June 20, 2017)

AOAC INTERNATIONAL COMMITTEE ON STATISTICS Draft Meeting Agenda Tuesday, June 20, 2017 Meeting Start Time: 11:00AM (Eastern US)

Chair: Sidney Sudberg (Alkemists Pharmaceuticals) ______________________________________________________________________________

( Need member to volunteer to take the minutes )

I. WELCOME & INTRODUCTION (Sudberg – 11:00AM‐11:10AM) *

Sidney Sudberg will call the meeting to order, welcome and introduce the members of Statistics Committee. Members will review the AOAC policy documents and vote on the draft meeting agenda.

II. REVIEW OF MEETING AGENDA & MINUTES (All – 11:10AM-11:15AM) * The members of the Statistics Committee will review and vote on the May 17, 2017 meeting minutes.

III.

CURRENT METHOD CONFORMITY ASSESSMENT PROJECTS (Wehling/LaBudde/Sudberg/Thompson/Graves – 11:15AM-11:35AM)

Progress updates a. Statistics for Microbiology Methods Validation - Paul Wehling & Robert LaBudde (Leads) 1. Progress for Internal Validation Plan 2. Next Subcommittee Meeting?

Volunteers: 1.

Caryn Thompson

4.

Mike Zapf

2.

Qian Graves

5.

Hilde Skår Norli

3.

Jane Weitzel

6.

Sidney Sudberg

b. Changes to Appendix J - Paul Wehling & Robert LaBudde (Leads) 1.

Quantitative methods need changes (performed during &/or after validation) a. Candidate minus Reference b. New method of calculating the CI for the paired DPod c. Use of Z (n) vs. t (n-1) d. Removal of reference to Welch/Satterthwaite t-test? e. Chi-Square Test Calculator (Robert/Paul) http://lcfltd.com/AOAC/aoac-binary-v2-5.xlsx i. To be handled with Appendix J changes

c. Statistics Committee’s Terms of Reference (ToR) 1. Latest version in progress – v.6 a. Review of Submitted Comments b. Staff to compile the changes as v.6

*Requires a vote

version 1

Draft meeting agenda is subject to change without notice