Statistics Meeting Book (June 20, 2018)

Improved confidence interval for difference in POD for two methods in a paired qualitative study

Robert A LaBudde Least Cost Formulations, Ltd And Paul Wehling (Presenter) Medallion Laboratories

AOAC Annual Meeting September 2016

copyright 2016 by Least Cost Formulations, Ltd., all rights reserved.

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Glossary • M1: first method used to detect analyte (typically ‘presumptive’ method) • M2: second method used to detect analyte (typically ‘confirmative’ method) • POD(M): probability (proportion) of analyte detections by method M • dPOD(M1,M2) = POD(M1) – POD(M2) • ‘Paired’: Both methods tested on same test portion

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copyright 2016 by Least Cost Formulations, Ltd., all rights reserved.