Statistics Meeting Book (May 17, 2017)

AOAC INTERNATIONAL COMMITTEE ON STATISTICS Draft Meeting Agenda Wednesday, May 17, 2017 Meeting Start Time: 11:00AM (Eastern US)

Chair: Sidney Sudberg (Alkemists Pharmaceuticals) ______________________________________________________________________________ ( Need member to volunteer to take the minutes )

I. WELCOME & INTRODUCTION (Sudberg – 11:00AM‐11:10AM) *

Sidney Sudberg will call the meeting to order, welcome and introduce the members of Statistics Committee. Members will review the AOAC policy documents and vote on the draft meeting agenda.

II.

REVIEW OF MEETING MINUTES (All – 11:10AM-11:15AM)* The members of the Statistics Committee will review and vote on the April 19, 2017 meeting minutes.

III.

CURRENT METHOD CONFORMITY ASSESSMENT PROJECTS (Wehling/LaBudde/Sudberg/Thompson/Graves – 11:15AM-11:35AM)

Progress updates a. Statistics for Microbiology Methods Validation (discuss internal validation plan) -Paul Wehling & Robert LaBudde (Leads)

1. Qian Graves has submitted some results 2. Mike Zapf and Hilde Skår Norli to compare notes 3. Need updates from the following: a. Jane Weitzel b. Caryn Thompson

Volunteers: 1. Caryn Thompson

4. Mike Zapf 5. Hilde Skår Norli 6. Sidney Sudberg

2. Qian Graves 3. Jane Weitzel

b. Changes to Appendix J -Paul Wehling & Robert LaBudde (Leads) 1. Quantitative methods need changes (performed during validation?) i. Candidate minus Reference ii. New method of calculating the CI for the paired DPod iii. Use of Z (n) vs. t (n-1) iv. Removal of reference to Welch/Satterthwaite t-test?

c. Chi-Square Test Calculator -All http://lcfltd.com/AOAC/aoac-binary-v2-5.xlsx 1. To be handled with Appendix J changes

*Requires a vote

version 1

Draft meeting agenda is subject to change without notice