the Stakeholder Panel on Dietary Supplements

SMPR Key Points

Validation Guidance Method must be able to separate SAMe from: 3. Other Ingredients Used in the Dietary Supplements  (Finished Products):  Vitamin C  Glutathione  Folic acid  B12

SMPR Key Points

Validation Guidance

STABILITY:  Method  developers must provide data 

demonstrating that SAMe remains stable in test  samples for the maximum time‐to‐determination.