2019 AOAC Annual Meeting - Preliminary Program

Improving the Measurement of Nutritional and Botanical Compounds: Strategies and Insights from NIST Quality Assurance Programs The U.S. National Institutes of Health (NIH) and National Institute of Standards and Technology (NIST) have collabo- ratively established laboratory Quality Assurance Programs (QAPs) for supporting improved measurements of vitamins, elements, fatty acids, bioactive and/or marker botanical compounds, and contaminants in a variety of commercial product and clinical matrices. Participant data from these intercomparison exercises is compiled at NIST and analyzed for accuracy, precision, and concordance within the commu- nity. Community-based performance reports and available one-on-one troubleshooting with NIST staff contribute to the QAP’s emphasis on analyst support and education. In addition to serving the needs of individual labs, the NIH/NIST QAP also affords an assessment of current community-wide measurement challenges and analytical needs. This symposium will report on insights gained from NIH/NIST QAP exercises, offering guid- ance on best practices and strategies to help improve laboratory performance in the measurement of nutritional and botanical compounds. Furthermore, speakers will highlight recent devel- opments in which NIH/NIST QAP exercises were leveraged to facilitate multi-lab validation data collection to establish new AOAC Official Methods of Analysis and to compare the capabilities of orthogonal methodologies for issues of botanical identification. Co-Chair : Adam Kuszak, National Institutes of Health Co-Chair : Melissa Phillips, U.S. National Institute of Standards and Technology Charles Barber, U.S. National Institute of Standards and Technology The Framework and Execution of the NIST Quality Assurance Programs Elizabeth Mudge, National Research Council Canada Leveraging Quality Assurance Programs for Multi-Lab Method Validation Studies Holly Johnson, American Herbal Products Association Leveraging Quality Assurance Programs to Assess the Analytical Community ‘State-of-the-Science’ The availability of accurate, fit for purpose reference materials (RMs) is necessary for analytical measurement. The most highly characterized RMs are those produced by national metrological institutes such as National Institute of Standards and Technology (NIST), LGC Group, NMI Australia, among others. However, use of these RMs can be problematic. There is often limited availability, they take multiple years to produce and they cannot fill the demand for calibration and quality control reference materials across all industries. Commercial reference material manufactures were started to meet this demand. To help ensure commercially made RM’s were fit for purpose, ISO developed ISO 17034:2016, which is a set of requirements that all CRM manufacturers must follow during production and quality control Certified Reference Materials: Advancements in Manufacturing and Stability

processes. Among other requirements, ISO 17034 specifies the proper characterization and uncertainty determination of the CRM. Certain aspects of the uncertainty and characterization will be discussed as it relates to various industry demands. Chair : Don Shelly, LGC Standards Daniel Biggerstaff, LGC Standards Improvements in Stability of Large Custom Certified Reference Material Mixtures Joe Konschnik, Restek Corporation Unlocking the Mystery of Pesticides CRM Stability for Food Analysis Laura Wood, U.S. National Institute of Standards and Technology Authenticity and Safety; Evaluating the Stability and Homogeneity of In-House Reference Materials 3:00 pm – 4:30 pm Cannabis and Cannabis Byproducts—An Update on the State of Industry and Current Challenges The legalized cannabis market, which includes hemp and mari- juana, whether recreational or medical continues to grow and change. As new states legalize cannabis, cannabis entities are expanding at a rapid rate. State regulatory bodies are attempt- ing to keep up with the industry’s capitalist nature which has produced a diverse and extensive range of products designed to meet client needs through a vast array of products and in a number of mainstream and niche markets. Strict state and municipal regulations exist and are designed to keep consumers safe. Some studies have found inconsistencies in potency levels in these products and concerns about potential biocontaminants exist. The session’s objective is to provide an overview of current safety issues facing cannabis edibles and how industry is looking to mitigate them. Co-Chair : Patrick Bird, AOAC Technical Consultant Co-Chair : Seth Wong, TEQ Analytical Labs Seth Wong, TEQ Analytical Labs Basics of Cannabis Products and By-Products Heather Krug, Colorado Department of Public Health and Environment Cannabis in Edibles and Other Products 5 Years Later – Lessons Learned and Future Concerns Melissa Phillips, U.S. National Institute of Standards and Technology Overcoming Challenges in Development of Cannabis Reference Materials Mike Clark, Bio-Rad Laboratories Implementation of New and Novel Approaches to Microbial Testing of Cannabis and Cannabis Infused Products Toby Astill, PerkinElmer, Inc. Cannabis and Cannabis Byproducts: An Update on the State of Industry and Current Challenges

26 SEPTEMBER 6–12, 2019 SHERATON DENVER DOWNTOWN HOTEL