AOAC 2018 Preliminary Program

Symposium: Statistical Tools for Improving Laboratory and Collaborative Study Methodologies This Symposium will address 1. recent changes to ISO 17025 and how Statistical evaluation is affected, 2. an update on the systematic review and meta-analysis of quantitative chemical collaborative studies, 3. demonstrate a statistical analysis of a published collaborative study using the pC metamer and 4. review an example of how a Statistical analysis of a proficiency test dataset can be used for the estimation of reproducibility or 5. “Equivalency of DNA sequencing vs. HPTLC chromato- graphic analysis vs. Botanical Microscopy methodologies for Review an Example of How a Statistical Analysis of a Proficiency Test Dataset Can Be Used for the Estimation of Reproducibility • Sidney Sudberg, Alkemists Laboratories An Update on the Systematic Review and Meta-Analysis of Quantitative Chemical Collaborative Studies • Sidney Sudberg, Alkemists Laboratories Demonstrate a Statistical Analysis of a Published Collaborative Study Using the pC metamer • Jane Weitzel, Consultant Statistical Tools to Meet ISO/IEC17025:2017 Requirements • Sidney Sudberg, Alkemists Laboratories Equivalency of DNA Sequencing vs. HPTLC Chromatographic Analysis vs. Botanical Microscopy Methodologies for Botanical Identity: A Statistical Evaluation 10:15 am – 11:45 am Symposium: What Does Gluten Mean from the Analytical Perspective? Many jurisdictions have definitions for gluten-free, and the majority has established a threshold level of 20 mg gluten / kg food. Analytical methods are the main tools for food produc- ers to ensure compliance. The ones most widely used are Immunoassays, ELISA and LFD, based on different antibodies, e.g. R5, G12 or Skerritt. LC-MS/MS applications have also been developed for the detection of gluten, although their commer- cial use is rather limited. Considering the complexity of gluten, the different specificity of existing methods and the use of different assay calibrators, can analytical results be aligned with the regulatory definition of gluten-free? CO-CHAIR: Carmen Diaz-Amigo, FOCOS GbR CO-CHAIR: Girdhari Sharma, U.S. Food and Drug Administration • Girdhari Sharma, U.S. Food and Drug Administration Gluten Detection beyond Analytical Method: Sampling Considerations • Markus Lacorn, R-Biopharm AG Gluten Measurement by the R5 Monoclonal Antibody: Past, Present and Future Botanical Identity: A Statistical Evaluation.” CHAIR: Sidney Sudberg, Alkemists Laboratories • Qian Graves, U.S. Food and Drug Administration

• Angel Cebolla, Biomedal Uncovering the Exposure to Gluten Immunogenic Peptides with G12 Antibody Methods • Terry Koerner, Health Canada Detection and Quantification of Gluten by MS: Challenges with a Regulatory Limit Symposium: Ensuring Food Protection — New Analytical Advances in Detection Methods Bringing Routine Closer than Ever Food authenticity and fraud are topics of high interest in the food industry and tightly controlled by authorities and retailer codes of practice. The complexity of the food supply chain is challenging the abilities of analytical tools used for traceability of ingredients for food production. There remains significant interest in the analytical techniques to detect and help resolve supply chain issues. This symposium will feature interactive lectures on the advances in applied, phenotypic and genomic approaches. It will give an insight into non–targeted and targeted methods and provide information on rapid methods suitable for uptake by industry. We warmly invite you to attend this symposium, which brings together international experts in the fields of food authenticity and food integrity, as well as SMEs, and institutions, all having a stake in food authenticity and fraud to create transparency across the food value chain. This special mix of scientific and practical input to the symposium will be a valuable opportunity to grow your knowledge base, learn from practical experiences, and exchange ideas with peers. CO-CHAIR: Amanda Manolis, Thermo Fisher Scientific CO-CHAIR: Jessica Williams, Thermo Fisher Scientific • Ramin Khaksar, Clear Labs Practical Integration of NGS Technologies in Existing Food Safety Management Systems • Jesse Miller, NSF International Molecular Methods for Botanical Authentication and Adulteration Detection • Mario Gadanho, SGS North America, Inc. Next Generation Sequencing for Food Authenticity, Traceability and Safety • Amanda Manolis, Thermo Fisher Scientific Food Integrity with New Analytical Technologies: Unlocking the Truth Symposium: Which Multi-Class/Multi-Residue Method Strategies are Applicable for Veterinary Drug Residues Control in Foods? Multi-Target Screening and Multi- Confirmatory Quantification There have been needs and efforts from regulatory agencies and industries at national and international levels to develop and validate multi-class/multi-residue methods to screen and confirm veterinary drugs in food commodities. This scientific session provides updates from the scientists in the field on their recent achievements and challenges on the development of target screening and quantitative multi-class/multi-residue

20 AUGUST 26 – 29, 2018 SHERATON CENTRE TORONTO HOTEL