Amino-01 (July 2018)

Amino‐01 (July 2018) Method Evaluation Form (MEF)

0.545 0.566 0.572 0.580 0.594 0.595 0.575 0.581

‐0.035 ‐0.056 ‐0.062 ‐0.070 ‐0.084 ‐0.085 ‐0.065 ‐0.071 ‐0.066 0.015 ‐0.077 ‐0.061 0.029 0.119 ‐0.098 ‐0.071 0.040 0.037 ‐0.076 ‐0.043 ‐0.076 ‐0.065 0.040 0.094 ‐0.095 ‐0.064 0.022 0.031 ‐0.078 ‐0.058 ‐0.023 0.067

 FOR ERP USE ONLY DO NOT DISTRIBUTE

Mean   

0.576 0.015

SD   

Reference Material

Measured Results

T stat Bias

Difference from  certified value

CRM product

Analyte

Certified value Uncertainty Certified range Concentration

Confidence interval 

p ‐value

Nominal

0.837 0.821 0.731 0.641 0.858 0.831 0.720 0.723 0.836 0.803 0.836 0.825 0.720 0.666 0.855 0.824 0.738 0.729 0.838 0.818

NIST 1849A

Valine

0.76

0.11

0.65 ‐ 0.87

0.022

1.511

0.147

0.751 ‐ 0.814

Mean   

0.783 0.067

SD   

T stat =

d

/ sd

n

where:       = mean of the differences between measured results and reference value sd  = standard deviation of the differences between results and reference value n   =  number of replicate analyses of SRM d

H 0 :       = 0,   The null hypothesis is that there is no difference between the measured results and the certified value:

d

p ‐value: is the probability (at the 95% levels of confidence) of obtaining the test statistic assuming that the null hypothesis is true p ‐value < 0.05 indicate a difference of statistical signifance between measured results and SRM.

95% confidence interval: The true population of the measured value expected to fall within the confidence interval estimate 95% of the time

sd

sd

t crit

t crit

lower limit  = mean ‐

upper limit = mean +

n

n

crit t

where:           =  critical values of the t‐distribution

sd  = standard deviation of the differences between results an reference value n   =  number of replicate analyses of SRM

SPIFAN ERP Checklist v 1.6

27.06.2013