Amino-01 (July 2018)

Amino‐01 (July 2018) Method Evaluation Form (MEF)

Table 3

Precision ‐ repeatability.

 FOR ERP USE ONLY DO NOT DISTRIBUTE

Nr.  replicates  (n)

SPIFAN  Code

Product

Analyte

Conc. Level

Conc. Level

REQUIREMENTS SMPR

RSDr

RSD iR

RSDr

RSD iR

Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Child Formula Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder Infant Elemental Powder

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 6 6 6 6 6

His Tau Ser Arg Gly Asp Glu Thr Ala Pro Lys Tyr His Tau Ser Arg Gly Asp Glu Thr Ala Pro Lys Tyr His Tau Ser Arg Gly Asp Glu Thr Ala Pro Lys Tyr His Tau Ser Arg Gly Asp Glu Thr Ala Pro Lys Tyr His Tau Ser Arg Gly Asp Glu Thr Ala Pro Lys Tyr xCys Met Val Ile Leu Phe xCys Met Val Ile Leu Phe xCys Met Val Ile Leu Phe xCys Met Val Ile Leu Phe xCys Met Leu Phe His Tau Ser Arg Gly Val Ile

6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2 6 x 2

370.5

0.7% 4.9%

X

≤ Z % ≤ W %

0

N/A

N/A

All Analytes All Analytes

0.4‐5.0

10

15 10

883.75

0.7% 7.4% 0.5% 3.7% 0.6% 3.0% 0.9% 2.0% 0.6% 1.4% 0.3% 3.1% 0.5% 2.0% 0.4% 0.6% 1.0% 1.4% 0.5% 4.3% 1.0% 4.2% 0.3% 5.7% 2.0% 10.0% 1.7% 10.2% 0.5% 1.8% 0.7% 5.5% 0.4% 7.8% 0.6% 10.6% 0.4% 2.1% 1.1% 3.9% 1.5% 3.4% 0.6% 3.7% 0.6% 2.1% 0.9% 1.3% 0.3% 2.8% 0.6% 3.2% 1.6% 5.5% 0.5% 10.6% 0.7% 3.4% 0.3% 0.8% 0.3% 0.5% 0.3% 3.7% 0.7% 5.2% 1.2% 4.6% 0.2% 6.9% 0.8% 2.0% 1.0% 2.6% 1.4% 1.7% 0.6% 1.7% 0.4% 2.6% 1.2% 3.5% 0.5% 1.8% 0.5% 1.6% 1.6% 2.5% 0.9% 5.1% 0.8% 1.4% 1.1% 9.4% 1.3% 9.6% 0.5% 2.4% 1.2% 4.0% 3.7% 11.0% 0.7% 5.7% 1.9% 7.9% 1.7% 5.5% 2.3% 2.1% 2.0% 2.0% 0.6% 3.9% 1.7% 3.4% 1.4% 2.4% 3.0% 2.8% 1.8% 6.2% 3.1% 3.8% 1.6% 9.1% 1.5% 5.5% 1.9% 8.3% 1.4% 2.3% 2.0% 5.2% 1.9% 6.8% 0.6% 5.8% 1.5% 7.6% 1.9% 2.5% 0.7% 4.2% 1.0% 3.2% 0.6% 3.1% 0.8% 3.7% 0.9% 1.9% 0.9% 3.5% 0.9% 3.8% 0.0% 5.1% 1.7% 7.7% 2.6% 13.3% 3.4% 15.7% 1.0% 1.8% 1.8% 3.3% 0.5% 4.7% 1.2% 2.3% 1.0% 9.0% 1.3% 2.7% 0.4% 1.0% N/A N/A N/A N/A N/A N/A N/A N/A

>5.0

7

572

326.75 1422.75 3271.75

Those are the RSD R values from SMPR ^

716.5

579

1317.75 1290.25 680.5 159.25 342.75 761.75 1481.75 712.5 407.25 560.5 948.75 425.5 872 0

1783 2196

717 581

552.5 1078

839 202

371.75 1272.25

1105 1830 927.5 126.5

Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Protein Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Adult Nutritional RTF, High Fat Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based Infant Formula RTF, Milk Based

0

307.75 709.25

106 503

1237.75 252.5 218.75

519 491

267.5 59.25

138.75

326

274.25 584.25 258.75 195.75

0

448.75

244

141.75 581.25

1789 326.5

240.75 840.5 594.83

398 26.9

196.25 489.38 380.88 724.75 397.25

27

0

82.25 35.75

28

155.75 302.5 65.25 116.25 87

121

55.75 23.25 81.75 76.75 31.5

150.25 59.25 36.69 705.75 389.75 242.75 311

SRM 1849a SRM 1849a SRM 1849a SRM 1849a SRM 1849a

SPIFAN ERP Checklist v 1.6

27.06.2013