Food Authenticity Program Meeting Book (March 13, 2020)

Table A2: Expected Precision as a Function of Concentration-Repeatability

Analyte (%)

Analyte Ratio

Unit (%, mg/kg)

%RSD

% Mean Recovery

100

1.0

100 %

1.3 1.9 2.7 3.7 5.3 7.3

98-102 98-102 97-103 95-105 90-107 80-110 80-110 80-110 60-115 40-120

10

10 -1 10 -2 10 -3 10 -4 10 -5 10 -6 10 -7 10 -8 10 -9

10 %

1

1 %

0.01

0.1 %

0.001

100 mg/kg (ppm) 10 mg/kg (ppm) 1 mg/kg (ppm) 100 g/kg (ppb) 10 g/kg (ppb) 1 g/kg (1ppb)

0.0001 0.00001 0.000001 0.0000001 0.00000001

11 15 21 30

9

Definitions Multi-laboratory Validation (MLV) — Demonstration between laboratories using adulterated samples created by a third-party group and supplied blindly to the participating laboratories according to guidelines described by the AOACI [Reference Appendix Document] to be considered for classification as AOAC Final Action Method " Protocol for the design, conduct and interpretation of method performance studies ". Pure and Applied Chemistry, Horwitz, W. 1995. 67:331-343; " Guidelines for the Assessment of the Competence of Testing Laboratories Involved in the Import and Export Control of Food“- CAC/GL 27-1997 ; " Harmonized IUPAC Guidelines for the use of Recovery Information in Analytical Measurement" - CAC/GL 37-2001 ; see also " Harmonised Guidelines for the Use of Recovery Information in Analytical Measurement" Thompson, M., Ellison, S., Fajgelj, A., Willetts, P., & Wood, R. (1999) Pure Applied Chemistry, 71: 337-348.