ISPAM Stakeholder Panel Meeting Book 3-14-17

Scientific Basis for Gluten Policy

‰ Based on the best available information, it is anticipated that the majority of people with celiac disease will not be negatively affected if they limit their gluten intake to less than 10 mg per day.

‰ Exposure modelling was done based on 20 ppm gluten and a 10 mg per day limit.

11

11

Modelling Daily Gluten Exposure in a Gluten-Free Diet ‰ No information available on a “typical” gluten-free diet ‰ Instead, information on a typical Canadian diet was used o collected as part of “The Canadian Community Health Survey – Cycle 2.2 on Nutrition, Statistics Canada, 2004” o Used 24 hour dietary recall with 10786 respondents o Data was split into a variety of age/sex categories to reflect the fact that these groups typically eat different amounts ‰ The amount of gluten-containing grain products in the typical Canadian diet was analyzed using hypothetical levels of 5, 10, 20 and 50 ppm of gluten

12

12