ISPAM Stakeholder Panel Meeting Book 3-14-17

Table 1: Estimated Percentiles of Gluten Exposure (mg) assuming Gluten Contamination at a Level of 20ppm Age-Sex Groups 24-hour Intake Usual Intake 50 th percentile 97 th percentile 50 th percentile 97 th percentile 1 to 3 years 1.59 4.60 1.73 3.65 4 to 8 years 2.71 6.90 2.94 4.67 M - 9 to 13 years 3.30 8.48 3.75 5.66 F - 9 to 13 years 2.88 6.86 3.19 5.06 M - 14 to 18 years 3.67 10.12 4.13 7.12 F - 14 to 18 years 2.75 7.58 2.95 5.33 M - 19 to 30 years 3.35 10.31 3.71 6.30 F - 19 to 30 years 2.34 6.80 2.49 4.28 M – 31 to 50 years 2.89 8.95 3.31 6.47 F – 31 to 50 years 2.23 6.33 2.43 4.14 M – 51 to 70 years 2.70 7.10 2.86 5.36 F – 51 to 70 years 2.06 5.88 2.22 4.01 M – 71 or more years 2.51 6.75 2.72 4.81 F – 71 or more years 2.03 4.83 2.16 3.83 Overall 2.54 7.72 3.03 5.64 Daily Gluten Exposure Estimate at 20 ppm Gluten

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‰ 20 ppm gluten as an action level for substitute foods labelled as gluten-free should support restriction of usual gluten intake to less than 10 mg per day. Modelling Gluten Exposure in a Gluten-Free Diet Conclusions

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