Micro Community Meeting Book
Use for analysis of aerosol collection dry filter unit (DFU) filters as part of concept of operation-based routine testing to make actionable calls. Standard Method Performance Requirements (SMPRs ) for Detection of Multiple Biothreat Agent Organisms in Environmental Samples by Amplicon Sequencing Simultaneous detection of Bacillus anthracis , Francisella tularensis , Yersinia pestis , Burkholderia mallei , Burkholderia pseudomallei , Brucella abortus , Coxiella burnetii , and Variola virus from DFU filters or polytetrafluoroethylene (PTFE) filters.
A suitable method can target some or all of these agents as appropriate for the specific biodefense program or concept of operations.
New sequencing tools can provide a metagenomic non-targeted approach, but crically removing false positives will be more important
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